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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLXIPL
All Species:
6.06
Human Site:
S556
Identified Species:
10.26
UniProt:
Q9NP71
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NP71
NP_116569.1
852
93073
S556
T
L
L
R
S
P
G
S
P
Q
E
T
V
P
E
Chimpanzee
Pan troglodytes
XP_509441
819
90122
H526
A
P
G
V
P
E
F
H
S
S
I
L
V
T
D
Rhesus Macaque
Macaca mulatta
XP_001115131
390
43669
K119
L
K
L
L
C
R
D
K
I
R
L
N
N
A
I
Dog
Lupus familis
XP_546925
857
93734
S561
T
L
L
R
P
S
G
S
P
Q
E
M
A
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99MZ3
864
94857
Q568
L
R
P
P
E
S
P
Q
D
T
V
S
E
I
P
Rat
Rattus norvegicus
Q6AXT8
471
49872
N200
G
K
F
W
T
H
W
N
R
E
T
K
Q
F
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001104311
895
97370
D600
S
P
Q
S
S
V
P
D
V
P
A
V
F
L
P
Frog
Xenopus laevis
NP_001084764
548
60887
P277
G
N
A
D
M
I
Q
P
E
L
F
P
L
Q
P
Zebra Danio
Brachydanio rerio
XP_001338503
817
90800
D531
T
P
S
P
L
S
T
D
V
V
S
T
T
G
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724328
836
92381
S535
I
A
T
T
N
S
N
S
N
A
P
P
V
H
Y
Honey Bee
Apis mellifera
XP_394429
1014
115124
P717
T
T
H
H
I
T
T
P
V
T
V
Q
T
M
Q
Nematode Worm
Caenorhab. elegans
P41846
1009
112841
I618
P
I
S
R
T
S
T
I
F
G
N
V
E
N
K
Sea Urchin
Strong. purpuratus
XP_788672
1338
148936
T1018
R
P
E
G
G
S
C
T
P
V
R
T
V
V
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LVN1
1266
139556
S788
L
G
Q
T
R
A
P
S
A
P
P
P
P
P
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
41.6
42.9
87.7
N.A.
81.4
20.8
N.A.
N.A.
51.4
30.9
39.4
N.A.
20
29.5
25.5
21.1
Protein Similarity:
100
55.4
43.9
91.4
N.A.
85.7
29.3
N.A.
N.A.
60.7
41.6
53.5
N.A.
36.5
44.9
41.3
33.5
P-Site Identity:
100
6.6
6.6
73.3
N.A.
0
0
N.A.
N.A.
6.6
0
13.3
N.A.
13.3
6.6
6.6
20
P-Site Similarity:
100
13.3
13.3
73.3
N.A.
6.6
20
N.A.
N.A.
13.3
6.6
13.3
N.A.
20
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
0
0
8
0
0
8
8
8
0
8
8
0
% A
% Cys:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
15
8
0
0
0
0
0
8
% D
% Glu:
0
0
8
0
8
8
0
0
8
8
15
0
15
0
15
% E
% Phe:
0
0
8
0
0
0
8
0
8
0
8
0
8
8
15
% F
% Gly:
15
8
8
8
8
0
15
0
0
8
0
0
0
8
0
% G
% His:
0
0
8
8
0
8
0
8
0
0
0
0
0
8
0
% H
% Ile:
8
8
0
0
8
8
0
8
8
0
8
0
0
8
8
% I
% Lys:
0
15
0
0
0
0
0
8
0
0
0
8
0
0
8
% K
% Leu:
22
15
22
8
8
0
0
0
0
8
8
8
8
8
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
8
% M
% Asn:
0
8
0
0
8
0
8
8
8
0
8
8
8
8
0
% N
% Pro:
8
29
8
15
15
8
22
15
22
15
15
22
8
22
29
% P
% Gln:
0
0
15
0
0
0
8
8
0
15
0
8
8
8
8
% Q
% Arg:
8
8
0
22
8
8
0
0
8
8
8
0
0
0
0
% R
% Ser:
8
0
15
8
15
43
0
29
8
8
8
8
0
0
0
% S
% Thr:
29
8
8
15
15
8
22
8
0
15
8
22
15
8
0
% T
% Val:
0
0
0
8
0
8
0
0
22
15
15
15
29
8
0
% V
% Trp:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _